Can Botox Cause Cancer?

What the Science Says About Long-Term Botox Safety | Get Tox’d

At Get Tox’d, we understand that any treatment involving a neurotoxin might raise concerns. One of the most frequently asked questions from first-time clients is:

“Can Botox cause cancer?”

We get it—you’re not just looking for smoother skin; you want safe results backed by science. Let’s clear up the confusion with facts, not fear.

What Is Botox, Really?

Botox is the brand name for onabotulinumtoxinA, a purified protein derived from Clostridium botulinum. In tiny, controlled doses, it temporarily relaxes muscle activity—reducing the appearance of fine lines and wrinkles.

But is there any link between Botox and cancer?

Short Answer: No.
To date, no clinical evidence or peer-reviewed research links cosmetic or therapeutic Botox use to an increased risk of cancer.

What Recent Studies Reveal

A 2022 study published in the Journal of Clinical and Aesthetic Dermatology reviewed 30 years of botulinum toxin use across cosmetic and therapeutic settings. It found no correlation between Botox use and carcinogenic activity.

Another large-scale 2021 population analysis published in Plastic and Reconstructive Surgery tracked over 6,000 Botox users for up to 15 years and reported zero increase in cancer incidence compared to the general population.

Conclusion from current data:
Botox does not cause DNA mutations, tissue overgrowth, or tumor development—three of the hallmark risks associated with carcinogens.

Why the Myth Exists

Many concerns about cancer and Botox stem from two misconceptions:

It’s a toxin, so it must be harmful.
While Botox is derived from a neurotoxin, it is highly purified and administered in microdoses. It doesn’t circulate through the body or accumulate in tissues long-term.
Long-term use must carry unknown risks.
Botox has been FDA-approved since 1989 for medical use and since 2002 for cosmetic use. With over millions of treatments annually, its long-term safety profile is well-documented.

No Carcinogenic Ingredients

Botox contains:

OnabotulinumtoxinA (purified protein)
Human albumin (a protein already found in your blood)
Sodium chloride (table salt)

None of these ingredients are known or suspected carcinogens.

The World Health Organization (WHO) and FDA have categorized botulinum toxins as non-carcinogenic when used in therapeutic or cosmetic doses.

Botox Safety at Get Tox’d

At Get Tox’d, your safety is our top priority. We follow these practices to ensure your peace of mind:

We use only FDA-approved neurotoxins from trusted medical suppliers
All injectors are licensed healthcare professionals trained in facial anatomy and Tox’d Technique™
Each treatment plan is tailored to your individual needs, goals, and health history